Creatine isn’t new. You’re just late. I’ve watched it change brains and lives—long before anyone needed headlines.
What caught my attention:
🧠 Creatine + Alzheimer’s
“20g/day of creatine monohydrate for 8 weeks increased brain creatine by 11% in older adults with Alzheimer’s.”
The protocol was safe, 90% compliant, and marks the first human evidence of brain target engagement in AD.
Source: PMC ID: [PMC12050822] — Dr. William Wallace
⚡ Creatine is Safe + Essential at All Ages
“680+ studies confirm creatine is safe for all ages.”
2–4g daily enhances muscle strength, brain health, and cognition.
Higher intake (>1.5g/day) linked to greater height, lean mass, and bone strength in youth.
Low intake (<0.95g/day) linked to cognitive decline and increased depression risk.
Source: 2025, International Society of Sports Nutrition (ISSN) — Dr. William Wallace
🧠 Creatine + Brain Performance
“Creatine doses of 20g/day or 0.3g/kg/day for at least 7 days—or 4g/day for several months—increase total brain creatine levels in young and older adults.”
This improves:
Memory
Attention
Processing speed (in adults aged 18–60)
Source: PMID: [39070254], doi:10.1016/j.aehs.2024.05.002 — Dr. William Wallace
🧠 Creatine + Depression
“Creatine isn’t just for muscles.”
5g/day for 8 weeks significantly improved depressive symptoms in adults doing Cognitive Behavioral Therapy (CBT).
The improvement was clinically meaningful, with most participants seeing benefits.
Source: 2025, European Neuropsychopharmacology — PMID: [39488067] — Dr. William Wallace
What I see:
Creatine monohydrate is in my top five supplements of all time—and not just for performance.
For longevity.
For real, clinical, lasting change.
This is one of those supplements I plan to take for life.
Because let’s be honest—there’s no amount of beef or protein that’ll get you to optimal creatine levels.
You can survive off food intake alone. But you won’t thrive.
Especially if you’re vegetarian, vegan, or just not eating red meat consistently—you’re not getting enough. Period.
People think creatine is just a gym thing.No. It was marketed that way.
But the science has been here for years.The research is deep, real, peer-reviewed, and exploding now—but it's not new.
I’ve been using creatine for brain health in clinical settings for at least five years.
And I’ll never forget this one client last year—he had clinical depression for years.
Tracked his mood daily with an app. Couldn’t crack a smile. At best, he’d get to the “meh” neutral face for a few hours.
We tried everything.
Then I added 5g of creatine.
One week later?He had four consecutive days of actual smiley-face mood tracking.Four days. After years of nothing.
I shared this with my clinical team at the time and got laughed at.“Oh, creatine is for muscles,” they said.
Oh really? And now those same people are quoting the research like it’s gospel.
That’s the thing.You tell people something before it’s popular—they roll their eyes.
Then a longevity influencer posts the same thing, and suddenly it’s valid?
Let me be blunt:Don’t wait for the peanut gallery.
Don’t wait for some celebrity doctor to give you permission.Learn. Feel. Try.
I read the papers years ago.I tested it.I saw the change.Now the world is catching up.
And for the record—yes, it’s amazing for muscle, bone density, and peak performance too.
My kids take 10g a day.I take 10g a day.My cognitive function, brain spark, and memory are better now than ever before.This isn’t just working. It’s working better than anything else I’ve ever tried.And we’re not stopping. This is for life.
Because this isn’t just about gains.It’s about mood. Cognition. Longevity. Brain resilience.And knowing before it’s cool.